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Ignacio Varela Selected Research

Histones (Histone)

1/2018UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.

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Ignacio Varela Research Topics

Disease

16Neoplasms (Cancer)
11/2023 - 12/2009
5Progeria (Hutchinson Gilford Syndrome)
10/2011 - 12/2005
3Leukemia
01/2019 - 08/2014
3Carcinogenesis
11/2015 - 11/2014
3Pancreatic Neoplasms (Pancreatic Cancer)
01/2015 - 10/2010
2Chromothripsis
01/2020 - 01/2011
2Inflammation (Inflammations)
01/2017 - 10/2016
2Premature Aging
07/2008 - 12/2005
1Chronic Kidney Failure (Chronic Renal Failure)
06/2023
1Segmental glomerulosclerosis
06/2023
1Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
01/2022
1Mycosis Fungoides
01/2022
1Disease Progression
01/2022
1Lung Neoplasms (Lung Cancer)
01/2021
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2019
1B-Cell Leukemia (Leukemia, B Cell)
01/2019
1Rheumatoid Arthritis
01/2017
1Merkel Cell Carcinoma
01/2017
1Rheumatic Diseases (Rheumatism)
10/2016
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2016
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
01/2016
1Genetic Translocation (Chromosomal Translocation)
01/2016
1Hepatocellular Carcinoma (Hepatoma)
11/2015
1Cholangiocarcinoma
11/2015
1Lymphatic Metastasis
01/2015
1Inborn Genetic Diseases (Disease, Hereditary)
03/2014
1Endometrial Neoplasms (Endometrial Cancer)
07/2013
1Neoplasm Metastasis (Metastasis)
10/2010
1Breast Neoplasms (Breast Cancer)
01/2010
1Alopecia (Baldness)
07/2008
1Lipodystrophy
07/2008
1Genomic Instability
12/2005

Drug/Important Bio-Agent (IBA)

6Proteins (Proteins, Gene)FDA Link
01/2021 - 07/2008
6DNA (Deoxyribonucleic Acid)IBA
01/2016 - 12/2009
5ChromatinIBA
01/2021 - 12/2005
3Transcription Factors (Transcription Factor)IBA
11/2023 - 01/2015
2Small Cytoplasmic RNAIBA
03/2021 - 01/2020
2NucleotidesIBA
01/2020 - 01/2016
2Toll-Like Receptors (Toll-Like Receptor)IBA
01/2017 - 10/2016
2Biomarkers (Surrogate Marker)IBA
01/2017 - 03/2012
2prelamin AIBA
10/2011 - 07/2008
2Lamin Type A (Lamin A)IBA
12/2010 - 12/2005
2Peptide Hydrolases (Proteases)FDA Link
12/2010 - 12/2005
1Glycoproteins (Glycoprotein)IBA
06/2023
1Protein Kinase C-thetaIBA
01/2022
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2022
1CytokinesIBA
01/2022
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
01/2021
1RNA (Ribonucleic Acid)IBA
01/2019
1Histones (Histone)IBA
01/2018
1Carrier Proteins (Binding Protein)IBA
01/2017
1AntibodiesIBA
10/2016
1AntigensIBA
10/2016
1Infliximab (Remicade)FDA Link
10/2016
1CRISPR-Cas Systems Guide RNAIBA
11/2015
1CateninsIBA
09/2015
1Recombinases (Recombinase)IBA
11/2014
13-Phosphoinositide-Dependent Protein KinasesIBA
11/2014
1CarcinogensIBA
10/2014
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
07/2013
1CytosineIBA
05/2012
1MicroRNAs (MicroRNA)IBA
06/2011
1Cadherins (E-Cadherin)IBA
01/2010
1Metalloproteases (Metalloproteinases)IBA
07/2008
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
07/2008
1LaminsIBA
12/2005

Therapy/Procedure

2Therapeutics
06/2023 - 01/2017
2Drug Therapy (Chemotherapy)
01/2021 - 02/2015
2Precision Medicine
03/2015 - 03/2012
1Transplantation
01/2016
1Transcutaneous Electric Nerve Stimulation (TENS)
01/2011